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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tfe3 - transcription factor E3
Alias:
Tcfe3
Tfe-3
mTFE3
bHLHe33
F830016E06Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性的DNA结合活性;以及蛋白质异二聚体化活性。参与几个过程,包括负调控冷诱导产热作用;正调控棕色脂肪细胞分化;以及通过RNA聚合酶II的正调控转录。在转录的正调控、DNA模板和破骨细胞分化的调控中起上游作用。位于细胞质和细胞核中。在包括脂肪组织、鳃弓、早期胎囊、生殖泌尿系统和肠道在内的几个结构中表达。该基因的人类同源物与肾细胞癌有关。与人类TFE3(与IGHM增强子结合的转录因子3)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:209446
ENSEMBL:ENSMUSG00000000134
UNIPROT:Q64092
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
209446
12
10
12673 bp
61.54
4
20
Tfe3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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