Enables nucleotide binding activity and sulfotransferase activity. Acts upstream of or within sulfation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in adrenal gland; central nervous system; gland; meninges; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including SULT1A1 (sulfotransferase family 1A member 1). [provided by Alliance of Genome Resources, Apr 2022]