Dis3l2 - DIS3 like 3'-5' exoribonuclease 2

Enables 3'-5'-exoribonuclease activity; magnesium ion binding activity; and poly(U) RNA binding activity. Involved in miRNA catabolic process and stem cell population maintenance. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; ganglia; metanephros; and nose. Used to study Perlman syndrome. Human ortholog(s) of this gene implicated in Perlman syndrome and nephroblastoma. Orthologous to human DIS3L2 (DIS3 like 3'-5' exoribonuclease 2). [provided by Alliance of Genome Resources, Apr 2022]