Akr1d1 - aldo-keto reductase family 1, member D1

Predicted to enable 3-oxo-5-beta-steroid 4-dehydrogenase activity; alditol:NADP+ 1-oxidoreductase activity; and ketosteroid monooxygenase activity. Predicted to be involved in cellular hormone metabolic process; cholesterol catabolic process; and digestion. Predicted to act upstream of or within bile acid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; heart; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 2. Orthologous to human AKR1D1 (aldo-keto reductase family 1 member D1). [provided by Alliance of Genome Resources, Apr 2022]