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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pde2a - phosphodiesterase 2A, cGMP-stimulated
Alias:
cGSPDE
CGS-PDE
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活多种功能,包括3',5'-环核苷酸磷酸二酯酶活性;GAF结构域结合活性;和环核苷酸结合活性。参与多种过程,包括cGMP分解过程;环核苷酸介导的信号传导;和细胞内信号传导的负调控。在脂质多糖的细胞响应的上游或内部发挥作用;循环系统发育;和一氧化氮介导的信号传导的调控。位于几个细胞组件中,包括线粒体;核周质;和突触前膜。在几个结构中表达,包括泌尿生殖系统;肠道;血细胞系统;神经系统;和感觉器官。与人类的PDE2A(磷酸二酯酶2A)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:207728
ENSEMBL:ENSMUSG00000030653
UNIPROT:Q922S4
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
207728
16
31
91122 bp
105.62
7
13
Pde2a Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
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