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Sephs2 - selenophosphate synthetase 2

Alias:
Sps2
Ysg3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种酶,该酶催化从硒化物和ATP产生单硒磷酸盐(MSP)。MSP是合成硒半胱氨酸(Sec)所需的硒供体,硒半胱氨酸是在读码框内UGA密码子处共翻译地结合到硒蛋白质中,该密码子通常作为翻译终止信号。硒蛋白质mRNA的3'UTR含有保守的茎环结构,即Sec插入序列(SECIS)元素,该元素对于识别UGA作为Sec密码子而不是作为停止信号是必要的。该蛋白质本身是一种含有活性位点Sec残基的硒蛋白质,这表明存在一种自调节机制。它优先在参与硒蛋白质合成的组织中和血细胞发育部位表达。[由RefSeq,2017年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
1
2181 bp
47.83
3
5

Sephs2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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