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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sox2 - SRY (sex determining region Y)-box 2
Alias:
lcc
ysb
Sox-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个无内含子的基因编码SRY相关HMG盒(SOX)家族的一员,该家族参与胚胎发育的调节和细胞命运的确定。这个基因的产物是中枢神经系统中干细胞维持所必需的,并调节胃中的基因表达。人类中类似基因的突变与视神经发育不良和综合征性小眼症有关,这是一种严重的眼部结构畸形。这个基因位于另一个称为SOX2重叠转录(Sox2ot)的基因的内含子里。[RefSeq,2015年9月提供]
Related ID:
NCBI:20674
ENSEMBL:ENSMUSG00000074637
UNIPROT:P48432
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20674
1
1
2467 bp
34.45
32
17
Sox2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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No data available
References Literature
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IF
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