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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Snap25 - synaptosomal-associated protein 25
Alias:
sp
Bdr
SUP
GENA70
SNAP-25
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
可激活SNAP25的绑定活性。参与突触体释放、神经递质受体内化以及神经元突起发育的调节。在几个过程的上游或内部发挥作用,包括关联学习、神经递质分泌和突触可塑性的调节。位于几个细胞组件中,包括谷氨酸能突触、突触囊泡和高尔基网络。是质膜细胞侧的外部组件。是突触素2-SNAP-25-语法蛋白1a-补蛋白1复合物的一部分。在肾上腺、颌、神经系统和感觉器官中表达。用于研究注意力缺陷多动障碍、肥胖症、精神分裂症和2型糖尿病。该基因的人类同源物与唐氏综合症和先天性肌无力综合症18有关。与人类SNAP25(突触相关蛋白25)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20614
ENSEMBL:ENSMUSG00000027273
UNIPROT:P60879
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20614
13
8
68990 bp
23.32
12
29
Snap25 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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