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中文小鼠
Smpd1 - sphingomyelin phosphodiesterase 1, acid lysosomal
Alias:
ASM
aSMase
A-SMase
Zn-SMase
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激活酸性鞘磷脂磷酸二酯酶活性和锌离子结合活性。参与神经酰胺生物合成过程；对凋亡过程的正向调节；以及对电离辐射的反应。在神经酰胺代谢过程、胆固醇代谢过程和鞘磷脂分解代谢过程的上游或内部发挥作用。位于细胞外空间。在包括消化系统、皮肤系统、神经系统、感觉器官和骨架在内的几个结构中表达。用于研究Niemann-Pick病。此基因的人类同源物与Niemann-Pick病、Niemann-Pick病A型和Niemann-Pick病B型有关。与人类SMPD1（鞘磷脂磷酸二酯酶1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Smpd1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
