Slc19a1 - solute carrier family 19 (folate transporter), member 1

Enables folic acid transmembrane transporter activity and methotrexate transmembrane transporter activity. Involved in folate import across plasma membrane and methotrexate transport. Located in apical plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cleft lip; dextro-looped transposition of the great arteries; hematologic cancer; and malaria. Orthologous to human SLC19A1 (solute carrier family 19 member 1). [provided by Alliance of Genome Resources, Apr 2022]