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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
EPHB4 - EPH Receptor B4
Alias:
HTK
MYK1
HFASD
CMAVM2
LMPHM7
TYRO11
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
Ephrin受体及其配体,ephrin,调节许多发育过程,特别是在神经系统中。根据其结构和序列关系,ephrin分为ephrin-A(EFNA)类和ephrin-B(EFNB)类,其中ephrin-A类通过糖基磷酰肌醇连接固定在膜上,而ephrin-B类是跨膜蛋白。Eph家族受体根据其细胞外结构域序列相似性和与ephrin-A和ephrin-B配体的结合亲和力分为两组。Ephrin受体是受体酪氨酸激酶(RTK)家族的最大亚群。此基因编码的蛋白质与ephrin-B2结合并在血管发育中起到基本作用。[RefSeq,2008年7月提供]
Related ID:
NCBI:2050
ENSEMBL:ENSG00000196411
HGNC:3395
UNIPROT:P54760
OMIM:600011
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2050
2
17
24959 bp
108.27
603
8
9
25
EPHB4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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