Enables sodium ion transmembrane transporter activity. Involved in sodium ion transport. Located in apical plasma membrane and cytosol. Is expressed in metanephros. Used to study Gitelman syndrome. Human ortholog(s) of this gene implicated in Gitelman syndrome and essential hypertension. Orthologous to human SLC12A3 (solute carrier family 12 member 3). [provided by Alliance of Genome Resources, Apr 2022]