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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
EPHB2 - EPH Receptor B2
Alias:
DRT
EK5
ERK
CAPB
Hek5
PCBC
EPHT3
Tyro5
BDPLT22
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码 Eph 受体家族的一种跨膜糖蛋白酪氨酸激酶。这些受体由 N 端糖基化的配体结合域、跨膜区和细胞内激酶域组成。它们与称为 Ephrin 的配体结合,并参与包括运动、分裂和分化在内的多种细胞过程。Eph-Ephrin 信号的一个区别特征是受体和配体都能传导信号级联,从而产生双向信号。这个蛋白属于 Eph 受体的一个亚组,称为 EphB。这个亚组的蛋白与其他家族成员的区别在于序列同源性和对膜结合 Ephrin-B 配体的偏好亲和力。等位变异与前列腺和脑癌易感性有关。替代剪接导致多种转录变体。[由 RefSeq 提供,2015 年 5 月]
Related ID:
NCBI:2048
ENSEMBL:ENSG00000133216
HGNC:3393
UNIPROT:P29323
OMIM:600997
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2048
7
16
210663 bp
117.49
78
3
12
21
EPHB2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
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No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
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No data available
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Name
CAS Number
Status
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Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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