人类

EPHB2 - EPH Receptor B2

Alias:
DRT
EK5
ERK
CAPB
Hek5
PCBC
EPHT3
Tyro5
BDPLT22
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码 Eph 受体家族的一种跨膜糖蛋白酪氨酸激酶。这些受体由 N 端糖基化的配体结合域、跨膜区和细胞内激酶域组成。它们与称为 Ephrin 的配体结合,并参与包括运动、分裂和分化在内的多种细胞过程。Eph-Ephrin 信号的一个区别特征是受体和配体都能传导信号级联,从而产生双向信号。这个蛋白属于 Eph 受体的一个亚组,称为 EphB。这个亚组的蛋白与其他家族成员的区别在于序列同源性和对膜结合 Ephrin-B 配体的偏好亲和力。等位变异与前列腺和脑癌易感性有关。替代剪接导致多种转录变体。[由 RefSeq 提供,2015 年 5 月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
16
210663 bp
117.49
78
3
12
21

EPHB2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top