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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
EPHA8 - EPH Receptor A8
Alias:
EEK
EK3
HEK3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码了酪氨酸激酶家族的 Ephrin 受体亚家族的成员。 Eph 和 Eph 相关受体已被发现介导发育事件,特别是在神经系统中。 Eph 家族的受体通常有一个酪氨酸激酶域和一个富含半胱氨酸的区域以及两个纤维连接蛋白 III 重复序列的外周区域。 Ephrin 受体根据其外周区域序列的相似性和与 Ephrin-A 和 Ephrin-B 配体的亲和力被分为两组。这个基因编码的蛋白质作为 Ephrin A2、A3 和 A5 的受体,在哺乳动物神经系统发育过程中发挥短程接触介导轴突导向的作用。 [由 RefSeq 提供,2008 年 7 月]
Related ID:
NCBI:2046
ENSEMBL:ENSG00000070886
HGNC:3391
UNIPROT:P29322
OMIM:176945
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2046
7
17
40107 bp
111.00
70
--
3
10
EPHA8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Status
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Link
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References Literature
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