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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sgk1 - serum/glucocorticoid regulated kinase 1
Alias:
Sgk
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种丝氨酸/苏氨酸蛋白激酶,在细胞应激反应中扮演重要角色。这个激酶激活某些钾、钠和氯通道,暗示其参与细胞存活、神经元兴奋性和肾钠排泄等过程的调节。这个酶通过蛋白质磷酸化激活,并通过泛素化和蛋白酶体途径降解。已发现这个基因有多个编码不同异型的转录变异体。在这个基因的一个假基因在染色体12上被鉴定。[由RefSeq, 2009年9月提供]
Related ID:
NCBI:20393
ENSEMBL:ENSMUSG00000019970
UNIPROT:Q9WVC6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20393
6
14
117720 bp
48.93
7
17
Sgk1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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