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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Spi1 - spleen focus forming virus (SFFV) proviral integration oncogene
Alias:
Dis1
PU.1
Dis-1
Sfpi1
Spi-1
Sfpi-1
Tcfpu1
Tfpu.1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录因子活性,RNA聚合酶II特异性;NFAT蛋白结合活性;以及组蛋白脱乙酰酶结合活性。参与多个过程,包括淋巴细胞分化;基因表达调控;以及髓样白细胞介导的免疫调控。在几个过程的上游或内部发挥作用,包括涉及血管形态发生;造血作用;以及转录调控的程序性细胞死亡过程。位于染色质和细胞核中。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;血细胞系统;以及呼吸系统。用于研究急性髓性白血病。与人类SPI1(Spi-1原癌基因)正链同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20375
ENSEMBL:ENSMUSG00000002111
UNIPROT:P17433
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20375
3
5
33355 bp
31.35
27
16
Spi1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
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References Literature
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