小鼠

Selenow - selenoprotein W

Alias:
selW
Sepw1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因编码一种含有硒半胱氨酸(Sec)残基的硒蛋白,该残基由正常作为翻译终止信号的UGA密码子编码。硒蛋白mRNA的3'UTR含有保守的茎环结构,即Sec插入序列(SECIS)元素,该元素对于将UGA识别为Sec密码子而非终止信号是必要的。该蛋白在骨骼肌和大脑中高度表达。它属于SelWTH家族,该家族具有类似硫氧还蛋白的折叠结构和一个保守的CxxU(C是半胱氨酸,U是Sec)基序,已被证明在体内具有谷胱甘肽依赖的抗氧化功能。小鼠研究提示,该硒蛋白参与肌肉生长和分化,以及保护神经元免受神经发育过程中的氧化应激。[RefSeq,2017年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
6
5164 bp
9.69
8
8

Selenow Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
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Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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