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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sel1l - sel-1 suppressor of lin-12-like (C. elegans)
Alias:
Sel1h
mKIAA4137
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
泛素蛋白转移酶活性。参与ERAD途径、蛋白质分泌和甘油三酯代谢过程。在内质网应激反应中起到上游或内部作用。位于内质网中。是Derlin-1逆转录复合物和Hrd1p泛素连接酶ERAD-L复合物的一部分。在包括泌尿系统、肝脏、神经管、胰腺和脾脏的几个结构中表达。该基因的人类同源物与胰腺癌有关。与人类SEL1L(ERAD E3泛素连接酶的ERAD适配器亚基)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20338
ENSEMBL:ENSMUSG00000020964
UNIPROT:Q9Z2G6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20338
2
21
43115 bp
88.34
6
14
Sel1l Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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