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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ccl2 - chemokine (C-C motif) ligand 2
Alias:
JE
HC11
MCAF
MCP1
MCP-1
Scya2
Sigje
SMC-CF
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是位于染色体11上的几个细胞因子基因之一。趋化因子是一类参与免疫调节和炎症过程的分泌性蛋白质超家族。该超家族根据成熟肽的N端半胱氨酸残基排列分为四个亚家族。这个趋化因子是CC亚家族的成员,其特点是两个相邻的半胱氨酸残基。这个细胞因子对单核细胞和记忆T细胞有化学吸引作用,但对中性粒细胞没有。人类同源物与以单核细胞浸润为特征的疾病发病机制有关,如银屑病、类风湿关节炎和动脉粥样硬化。[RefSeq,2015年9月提供]
Related ID:
NCBI:20296
ENSEMBL:ENSMUSG00000035385
UNIPROT:P10148
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
20296
1
3
1876 bp
16.33
11
13
Ccl2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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