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Ccl2 - chemokine (C-C motif) ligand 2

Alias:
JE
HC11
MCAF
MCP1
MCP-1
Scya2
Sigje
SMC-CF
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是位于染色体11上的几个细胞因子基因之一。趋化因子是一类参与免疫调节和炎症过程的分泌性蛋白质超家族。该超家族根据成熟肽的N端半胱氨酸残基排列分为四个亚家族。这个趋化因子是CC亚家族的成员,其特点是两个相邻的半胱氨酸残基。这个细胞因子对单核细胞和记忆T细胞有化学吸引作用,但对中性粒细胞没有。人类同源物与以单核细胞浸润为特征的疾病发病机制有关,如银屑病、类风湿关节炎和动脉粥样硬化。[RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
3
1876 bp
16.33
11
13

Ccl2 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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