Log In|Sign Up
中文人类
CTTN - Cortactin
Alias:
EMS1
Favorite
这个基因在乳腺癌和头颈部鳞状细胞癌中过度表达。编码的蛋白质定位于细胞质和细胞基底膜接触区域。这个基因有两个功能：(1)调节粘附型连接子组件之间的相互作用，(2)组织上皮和癌细胞细胞的细胞骨架和粘附结构。在凋亡过程中，编码的蛋白质以caspase依赖的方式降解。这个基因的异常调控有助于肿瘤细胞侵袭和转移。已经在这个基因中鉴定出三种编码不同异型体的剪接变异体。[RefSeq,2010年5月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CTTN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
