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中文人类
EMP2 - Epithelial Membrane Protein 2
Alias:
XMP
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这个基因编码PMP22/EMP家族的四个跨膜蛋白。编码的蛋白质调节细胞膜组成。它与各种功能有关，包括内吞作用、细胞信号传导、细胞增殖、细胞迁移、细胞粘附、细胞死亡、胆固醇稳态、尿白蛋白排泄和胚胎植入。已知它负调控caveolin-1，这是一种作为大多数细胞类型中洞状质膜凹陷主要成分的支架蛋白。通过激活PTK2，它正调控血管内皮生长因子A。它还调节血浆膜中特定整合素异构体的功能。这个基因的上调与多种不同组织的癌症进展有关。这个基因的突变与肾病综合症10型（NPHS10）有关。[由RefSeq，2015年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EMP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
