人类

APOBEC3A - Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A

Alias:
A3A
ARP3
PHRBN
bK150C2.1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是胞嘧啶脱氨酶基因家族的成员。在染色体22上发现的一组由七个相关基因或假基因组成的簇中,据认为这是由于基因复制而形成的。该簇的成员编码与其他家族成员相比,缺乏锌结合活性的蛋白质。该蛋白质在免疫方面发挥作用,限制外来DNA如病毒的传播。外来DNA限制的一种机制是将外来双链DNA胞嘧啶脱氨为尿嘧啶,从而导致DNA降解。然而,也认为其他机制涉及其中,因为抗病毒效果并不依赖于脱氨酶活性。已发现这个基因的两个转录变异体,编码不同的异构体。[RefSeq,2012年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
5
5576 bp
23.01
8
--
--
26

APOBEC3A Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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