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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
APOBEC3A - Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A
Alias:
A3A
ARP3
PHRBN
bK150C2.1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是胞嘧啶脱氨酶基因家族的成员。在染色体22上发现的一组由七个相关基因或假基因组成的簇中,据认为这是由于基因复制而形成的。该簇的成员编码与其他家族成员相比,缺乏锌结合活性的蛋白质。该蛋白质在免疫方面发挥作用,限制外来DNA如病毒的传播。外来DNA限制的一种机制是将外来双链DNA胞嘧啶脱氨为尿嘧啶,从而导致DNA降解。然而,也认为其他机制涉及其中,因为抗病毒效果并不依赖于脱氨酶活性。已发现这个基因的两个转录变异体,编码不同的异构体。[RefSeq,2012年7月提供]
Related ID:
NCBI:200315
ENSEMBL:ENSG00000128383
HGNC:17343
UNIPROT:P31941
OMIM:607109
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
200315
2
5
5576 bp
23.01
8
--
--
26
APOBEC3A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
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CAS Number
Status
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Link
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References Literature
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