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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Polr1a - polymerase (RNA) I polypeptide A
Alias:
mRPA1
194kDa
RPA194
Rpo1-4
2900087K15Rik
3010014K16Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活RNA聚合酶I活性和染色质结合活性。预测能参与DNA指导的5'-3' RNA聚合酶活性。预测与蛋白质定位至核仁及rRNA转录的负调控有关。位于染色体和细胞核中。是RNA聚合酶I复合物的一部分。在包括消化系统、大脑、早期胎囊、生殖系统和皮肤系统在内的几个结构中表达。这个基因的人类同源物与辛辛那提型面部骨骼发育异常有关。与人类POLR1A(RNA聚合酶I亚基A)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20019
ENSEMBL:ENSMUSG00000049553
UNIPROT:O35134
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20019
2
34
70383 bp
194.11
9
12
Polr1a Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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