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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ELF5 - E74 Like ETS Transcription Factor 5
Alias:
ESE2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种上皮细胞特异性的ETS家族转录因子。除了在其在调节角质细胞终末分化的后期阶段中的作用外,它似乎还调节许多在上皮组织中发现的上皮细胞特异性基因,如唾液腺和前列腺。由于其氨基端负调控结构域,它具有非常低的DNA亲和力。这个基因被认为是一种乳腺癌中的肿瘤抑制转录因子。[RefSeq,2022年5月提供]
Related ID:
NCBI:2001
ENSEMBL:ENSG00000135374
HGNC:3320
UNIPROT:Q9UKW6
OMIM:605169
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2001
6
7
35004 bp
31.26
16
--
6
6
ELF5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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