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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ELAVL1 - ELAV Like RNA Binding Protein 1
Alias:
HUR
Hua
MelG
ELAV1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是ELAVL家族RNA结合蛋白质的一员,该家族含有几个RNA识别基序,并选择性地结合位于mRNA 3'非翻译区中的AU丰富元素(AREs)。AREs信号指示mRNA的降解,作为调节基因表达的一种方式。因此,通过结合AREs,ELAVL家族蛋白质在稳定含有ARE的mRNA中发挥作用。这个基因与许多生物过程有关,并与许多疾病,包括癌症有关。它在许多癌症中高度表达,并且可能在癌症诊断、预后和治疗中具有潜在用途。[由RefSeq,2012年9月提供]
Related ID:
NCBI:1994
ENSEMBL:ENSG00000066044
HGNC:3312
UNIPROT:Q15717
OMIM:603466
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1994
3
6
47069 bp
36.09
3
--
11
38
ELAVL1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
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Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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