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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Rock1 - Rho-associated coiled-coil containing protein kinase 1
Alias:
Rock-I
1110055K06Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活Rho依赖的蛋白丝氨酸/苏氨酸激酶活性;天冬氨酸型内肽酶抑制剂活性;和小GTP酶结合活性。参与几个过程,包括肾小球内脏上皮细胞迁移;聚焦粘附组装的正调控;和血管紧张素响应。在几个过程的上游或内部发挥作用,包括顶部的收缩;小泡组装;和神经元凋亡过程的负调控。位于几个细胞成分中,包括胞质应激颗粒;膜下密度;和ruffle。在几个结构中表达,包括中枢神经系统;泌尿系统;肠道;心脏;和骨骼肌。与人类的ROCK1(Rho相关卷曲螺旋富含蛋白激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19877
ENSEMBL:ENSMUSG00000024290
UNIPROT:P70335
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
19877
2
33
117825 bp
158.17
16
19
Rock1 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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