人类

EIF4G2 - Eukaryotic Translation Initiation Factor 4 Gamma 2

Alias:
P97
AAG1
DAP5
NAT1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
翻译起始是由真核翻译起始因子4F(eIF4F)特异性识别帽子结构来介导的,eIF4F是一个由三个亚基组成的帽子结合蛋白复合物:eIF4A、eIF4E和eIF4G。这个基因编码的蛋白质与eIF4G的C端区域具有相似性,该区域包含与eIF4A和eIF3的结合位点;此外,eIF4G在N端还具有一个与eIF4E的结合位点。与支持依赖帽子和独立翻译的eIF4G不同,这个基因产物的功能是通过形成翻译不活跃的复合物来一般性地抑制翻译。在体外和体内研究中表明,这个mRNA的翻译起始唯一地在一个非AUG(GUG)密码子处开始。已经描述了编码这个基因的不同异构体的可变剪接转录变异体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
22
11881 bp
102.36
13
--
5
26

EIF4G2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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