人类

EIF4G1 - Eukaryotic Translation Initiation Factor 4 Gamma 1

Alias:
P220
EIF4F
EIF4G
EIF4GI
PARK18
EIF-4G1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是多功能蛋白质复合体EIF4F的组成部分。这个复合体促进mRNA被招募到核糖体,这是蛋白质合成起始阶段的一个限速步骤。该复合体中的因子催化mRNA帽和ATP依赖的5'-末端二级结构解旋。这个基因编码的亚基是一个大的支架蛋白质,含有与其他EIF4F复合体成员结合的位点。其N-端的一个结构域也可以与poly(A)-结合蛋白相互作用,这可能在翻译过程中调节mRNA的循环。选择性剪接产生多种转录变异体,其中一些来自选择性启动子用法。[RefSeq,2010年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
33
20753 bp
175.49
106
2
6
54

EIF4G1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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