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中文人类
EIF4EBP1 - Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Alias:
BP-1
4EBP1
4E-BP1
PHAS-I
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这个基因编码一个翻译抑制蛋白家族成员。该蛋白直接与真核翻译起始因子4E（eIF4E）相互作用，eIF4E是多亚基复合体的限制成分，将40S核糖体亚基招募到mRNA的5'端。这个蛋白与eIF4E的相互作用抑制复合物的组装并抑制翻译。这个蛋白可响应各种信号（包括紫外线照射和胰岛素信号）进行磷酸化，导致其从eIF4E解离并激活mRNA翻译。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EIF4EBP1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
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Residues
Reference
Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Mutations
Related Drugs
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CAS Number
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Link
References Literature
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Year
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