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中文人类
EIF4E - Eukaryotic Translation Initiation Factor 4E
Alias:
CBP
EIF4F
AUTS19
EIF4E1
eIF-4E
EIF4EL1
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这个基因编码的蛋白质是真核翻译起始因子4F复合体的组成部分，该复合体识别信使RNA 5'端的7-甲基鸟苷帽结构。编码的蛋白质通过将核糖体招募到5'帽结构中，有助于翻译的起始。这个蛋白质与4F复合体的结合是翻译起始过程中的限速步骤。这个基因作为一个原癌基因，其表达和激活与转化和肿瘤发生有关。在其他染色体上发现了这个基因的几个假基因。选择性剪接产生了多种转录变异体。[RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EIF4E Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
