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Ripk1 - receptor (TNFRSF)-interacting serine-threonine kinase 1

Alias:
RIP
Rinp
Rip1
RIP-1
D330015H01Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白质同二聚化活性和蛋白质丝氨酸/苏氨酸激酶活性。参与几个过程,包括坏死性信号通路;负调控心肌细胞增殖;以及信号传导的调控。在几个过程的上游或内部发挥作用,包括I-kappaB激酶/NF-kappaB信号传导的正调控;外在凋亡信号通路调控;以及参与坏死性过程的ripoptosome组装。预测位于几个细胞组件中,包括胞质;膜筏;和线粒体。预测是死亡诱导信号复合物;受体复合物;和ripoptosome的一部分。在几个结构中表达,包括中枢神经系统;心脏;肝脏;肺;和尾部。这个基因的人类同源物与免疫缺陷57有关。与人类RIPK1(受体相互作用丝氨酸/苏氨酸激酶1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
11
38082 bp
74.85
31
33

Ripk1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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