Rgs5 - regulator of G-protein signaling 5

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of vascular associated smooth muscle cell proliferation and signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm and membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and visual system. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human RGS5 (regulator of G protein signaling 5). [provided by Alliance of Genome Resources, Apr 2022]