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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Rgl1 - ral guanine nucleotide dissociation stimulator,-like 1
Alias:
Rgl
mKIAA0959
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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References Literature
这个基因编码Ras-like (Ral) -选择性鸟苷酸交换因子(RalGEF)家族的一员,这个家族的小GTP酶激活子既作为激活的Ras GTP酶的下游效应子,又作为RalGEF - Ral GTP酶信号通路中某些Ral GTP酶的调节剂。编码的蛋白质,与其他RalGEFs一样,具有N-末端ras交换器基序结构域,一个催化CDC25同源性结构域,和一个与Ral GTP酶结合时刺激鸟苷酸交换的C-末端ras结合结构域。RalGEF家族成员连接Ras和Ral信号通路,被认为在癌基因转化中起作用。可变剪接导致多个转录变异体。[RefSeq, 2016年9月提供]
Related ID:
NCBI:19731
ENSEMBL:ENSMUSG00000026482
UNIPROT:Q60695
Basic Information
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19731
8
19
249577 bp
86.32
3
7
Rgl1 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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