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Rgl1 - ral guanine nucleotide dissociation stimulator,-like 1

Alias:
Rgl
mKIAA0959
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码Ras-like (Ral) -选择性鸟苷酸交换因子(RalGEF)家族的一员,这个家族的小GTP酶激活子既作为激活的Ras GTP酶的下游效应子,又作为RalGEF - Ral GTP酶信号通路中某些Ral GTP酶的调节剂。编码的蛋白质,与其他RalGEFs一样,具有N-末端ras交换器基序结构域,一个催化CDC25同源性结构域,和一个与Ral GTP酶结合时刺激鸟苷酸交换的C-末端ras结合结构域。RalGEF家族成员连接Ras和Ral信号通路,被认为在癌基因转化中起作用。可变剪接导致多个转录变异体。[RefSeq, 2016年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
8
19
249577 bp
86.32
3
7

Rgl1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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