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Ret - ret proto-oncogene

Alias:
PTC
RET9
RET51
c-Ret
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活跨膜受体蛋白酪氨酸激酶活性。参与几个过程,包括Peyer斑发育、神经元细胞间粘附以及肾元肾小球发育的正调控。在几个过程的上游或内部发挥作用,包括动物器官发育、神经系统发育以及大分子代谢过程的正调控。预测位于几个细胞组分中,包括内质网、膜筏和神经元细胞体。预测是质膜蛋白复合物和受体复合物的组成部分。预测在轴突中活跃。预测是质膜的组成部分。在几个结构中表达,包括鳃弓、泌尿系统、肠道、神经系统和感器器官。用于研究Hirschsprung病、马蹄内翻足、多发性内分泌肿瘤2B型和嗜铬细胞瘤。该基因的人类同源物与Hirschsprung病、家族性髓质甲状腺癌、多发性内分泌肿瘤2A型、多发性内分泌肿瘤2B型和嗜铬细胞瘤有关。与人类的RET原癌基因(ret proto-oncogene)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
19
45997 bp
123.87
52
13

Ret Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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