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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Rela - v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Alias:
p65
p65 NFkB
p65 NF-kappa B
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录因子活性,特异性为RNA聚合酶II;肌动蛋白结合活性;以及锚蛋白重复序列结合活性。参与多种过程,包括蛋白质泛素化的负调控;突触后核信号通路;以及转录调控,基于DNA模板。在几个过程中起上游或内部作用,包括肝细胞生长因子刺激的细胞响应;脂多糖的细胞响应;以及正调控白细胞介素-12的生成。位于几个细胞成分中,包括染色质;胞质;以及谷氨酸能突触。在几个结构中表达,包括消化系统;早期胎囊;生殖泌尿系统;肌肉;以及皮肤。该基因的人类同源物与导管原位癌;非小细胞肺癌;淋巴瘤;以及肾细胞癌有关。与人类REL(REL原癌基因,NF-kB亚基)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19697
ENSEMBL:ENSMUSG00000024927
UNIPROT:Q04207
Basic Information
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Exons
Length
MW (kDa)
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Reference
19697
4
11
11170 bp
60.21
19
34
Rela Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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