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中文人类
EIF2S1 - Eukaryotic Translation Initiation Factor 2 Subunit Alpha
Alias:
EIF2
EIF-2
EIF2A
EIF-2A
EIF-2alpha
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翻译起始因子EIF2是蛋白质合成起始的第一个受调控的步骤，促进起始tRNA与40S核糖体亚基的结合。结合过程作为一个甲硫氨酸-tRNA、EIF2和GTP的三元复合物。EIF2由3个不同的亚基组成，即36kD的EIF2-alpha亚基（EIF2S1），38kD的EIF2-beta亚基（EIF2S2；MIM 603908）和52kD的EIF2-gamma亚基（EIF2S3；MIM 300161）。三元复合物的形成速度受EIF2-alpha磷酸化状态的影响（Ernst等人，1987年[PubMed 2948954]）。[由OMIM于2010年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
EIF2S1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
