人类

EGF - Epidermal Growth Factor

Alias:
URG
HOMG4
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个表皮生长因子超家族的成员。编码的前原蛋白在蛋白水解过程中被加工成53个氨基酸的表皮生长因子肽。这个蛋白作为一种强大的细胞有丝分裂因子,在多种细胞类型的生长、增殖和分化中扮演重要角色。这个蛋白通过与高亲和力的细胞表面受体,表皮生长因子受体结合来发挥作用。这个基因的缺陷是导致4型低镁血症的原因。这个基因的失调与某些癌症的生长和进展有关。选择性剪接导致多个转录变异体,至少其中一个编码在蛋白水解过程中被加工的前原蛋白。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
24
100884 bp
133.99
416
3
3
16

EGF Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top