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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Rasgrp1 - RAS guanyl releasing protein 1
Alias:
Rasgrp
calDAG-GEFII
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现多种功能,包括阳离子结合活性;二酯酰甘油结合活性;和鸟苷酸交换因子活性。参与胸腺中T细胞分化的正向调节和自然杀伤细胞分化的正向调节。在几个过程的上游或内部发挥作用,包括GTP酶活性的激活;肥大细胞脱颗粒;和磷酸肌醇3-激酶信号传导的调节。预测位于高尔基体;胞质;和质膜上。在大脑;嗅觉上皮;嗅觉皮层;和端脑披层表达。用于研究系统性红斑狼疮。这个基因的人类同源物与免疫缺陷64有关。与人类RASGRP1(RAS鸟苷酸释放蛋白1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19419
ENSEMBL:ENSMUSG00000027347
UNIPROT:Q9Z1S3
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19419
1
17
62895 bp
90.30
13
22
Rasgrp1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
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