小鼠

Rac2 - Rac family small GTPase 2

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活GTP酶活性和蛋白质激酶调节活性。参与膜下层组装的正调控;调控白细胞激活;以及调控白细胞趋化性。在几个过程的上游或内部发挥作用,包括G蛋白偶联受体信号通路;肌动蛋白细胞骨架组织;以及细胞突起组装。位于细胞质;膜;和核膜。在心表达。用于研究中性粒细胞趋化性缺陷和淋巴细胞减少的免疫缺陷73b。该基因的人类同源物与中性粒细胞趋化性缺陷和白细胞增多症、中性粒细胞趋化性缺陷和淋巴细胞减少的免疫缺陷73b以及中性粒细胞趋化性缺陷和低丙种球蛋白血症的免疫缺陷73c有关。与人类RAC2(Rac家族小GTP酶2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
7
13615 bp
21.44
10
5

Rac2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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