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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ptpro - protein tyrosine phosphatase, receptor type, O
Alias:
D28
PTPBK
PTPU2
PTPoc
GLEPP1
PTPROt
PTPphi
Ptpn15
R-PTP-O
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活Wnt蛋白结合活性;蛋白质同二聚化活性;蛋白质酪氨酸磷酸酶活性。参与几个过程,包括肽基-酪氨酸脱磷酸化,涉及蛋白激酶活性的失活;质膜结合的细胞突起组织;和裂隙状隔膜组装。位于几个细胞组件中,包括顶质膜;谷氨酸能突触;和侧质膜。在GABA能突触中活性。是突触后密度膜的整合成分。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;免疫系统;和脊髓。这个基因的人类同源物与肾病综合症6型有关。与人类PTPRO(蛋白质酪氨酸磷酸酶受体类型O)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19277
ENSEMBL:ENSMUSG00000030223
UNIPROT:E9Q612
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19277
9
27
211063 bp
138.59
7
6
Ptpro Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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