Ptpre - protein tyrosine phosphatase, receptor type, E

Enables identical protein binding activity and protein tyrosine phosphatase activity. Involved in negative regulation of insulin receptor signaling pathway and regulation of mast cell activation. Acts upstream of or within transmembrane receptor protein tyrosine phosphatase signaling pathway. Located in cytoplasm and plasma membrane. Is expressed in midbrain and superior colliculus. Orthologous to human PTPRE (protein tyrosine phosphatase receptor type E). [provided by Alliance of Genome Resources, Apr 2022]