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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
AGO3 - Argonaute RISC Catalytic Component 3
Alias:
EIF2C3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码了一个在RNA干扰中发挥作用的Argonaute家族蛋白质的成员。编码的蛋白质高度碱性,包含一个PAZ域和一个PIWI域,可能在由短干扰RNA介导的基因沉默中发挥作用。这个基因位于1号染色体上,与argonaute 4和真核翻译起始因子2C, 1等密切相关家族成员组成一个串联簇。已经鉴定了这个基因的两种转录变体,编码不同的等位基因。[由RefSeq提供,2008年7月]
Related ID:
NCBI:192669
ENSEMBL:ENSG00000126070
HGNC:18421
UNIPROT:Q9H9G7
OMIM:607355
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
192669
9
19
141783 bp
97.36
33
--
4
12
AGO3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
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Score
Mutations
No data available
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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Status
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Link
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References Literature
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