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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ptprc - protein tyrosine phosphatase, receptor type, C
Alias:
loc
B220
Cd45
L-CA
Ly-5
T200
CD45R
Lyt-4
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括硫酸肝素蛋白聚糖结合活性;肝素结合活性;和蛋白质酪氨酸磷酸酶活性。参与多个过程,包括淋巴细胞分化;宏分子代谢过程的正向调节;和信号传导的调节。在几个过程的上游或内部发挥作用,包括淋巴细胞分化;淋巴细胞激活的正向调节;和蛋白质磷酸化的调节。位于质膜的外侧;粘着斑;和膜筏。在几个结构中表达,包括第三鳃弓;消化系统;心血管系统;血细胞系统;和胎盘。用于研究系统性红斑狼疮。此基因的人类同源物与丙型肝炎;多发性硬化症;严重联合免疫缺陷;和严重联合免疫缺陷,常染色体隐性,T细胞阴性,B细胞阳性,Nk细胞阳性有关。与人类PTPRC(C型蛋白质酪氨酸磷酸酶受体)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:19264
ENSEMBL:ENSMUSG00000026395
UNIPROT:P06800
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19264
9
32
112895 bp
144.84
32
21
Ptprc Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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