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Ptpn22 - protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

Alias:
PEP
Ptpn8
70zpep
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活SH3结构域结合活性和激酶结合活性。参与几个过程,包括调节T细胞激活;调节细胞因子产生;以及调节信号传导。在T细胞分化上游或内部发挥作用;T细胞受体信号通路;以及蛋白质脱磷酸化。位于细胞质;质膜的细胞质侧;以及核内。在背根神经节;周围神经系统;和胸腺原基中表达。这个基因的人类同源物涉及几种疾病,包括阿迪森病;梅尼埃病;自身免疫性疾病(多种);慢性淋巴细胞白血病;和肺结核。与人类PTPN22(非受体型蛋白酪氨酸磷酸酶22)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
9
22
55678 bp
89.71
17
11

Ptpn22 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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