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中文小鼠
Ptpn1 - protein tyrosine phosphatase, non-receptor type 1
Alias:
PTP1B
PTP-1B
PTP-HA2
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预测能够实现几个功能，包括蛋白磷酸酶2A结合活性；信号受体结合活性；和锌离子结合活性。涉及几个过程，包括IRE1介导的未折叠蛋白响应；信号传导的负调控；和参与蛋白激酶活性失活的肽基-酪氨酸去磷酸化。在胰岛素受体信号通路和蛋白去磷酸化上游发挥作用。位于早期内体和高尔基体。在中枢神经系统；中脑；和上柱状上皮表达。这个基因的人类同源物与2型糖尿病有关。与人类PTPN1（非受体型1型蛋白酪氨酸磷酸酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ptpn1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
