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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pthlh - parathyroid hormone-like peptide
Alias:
PLP
Pthrp
PTH-like
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码甲状旁腺激素家族的一员,具有明显的旁分泌和自分泌信号传导作用,如循环钙调节、胎盘钙转运、破骨细胞抑制、肾碳酸氢盐排泄和细胞凋亡调节。编码的蛋白质经过蛋白酶降解处理,生成具有不同信号传导功能的多个活性肽。这个基因的纯合缺失导致出生后立即死亡,伴有软骨营养不良表型,特点是软骨细胞分化过早和骨形成加速。[RefSeq,2015年7月提供]
Related ID:
NCBI:19227
ENSEMBL:ENSMUSG00000048776
UNIPROT:P22858
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19227
1
4
11905 bp
Unknown
9
2
Pthlh Genetics information (-)
GRCm39
Chr : -
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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