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中文小鼠
Ptgs2 - prostaglandin-endoperoxide synthase 2
Alias:
COX2
Cox-2
PES-2
PHS-2
Pghs2
TIS10
PGHS-2
PHS II
gripghs
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这个基因编码一种属于前列腺素G/H合酶家族的酶。编码的蛋白质将花生四烯酸转化为前列腺素内过氧化物H2，这是前列腺素生物合成中的关键酶促步骤。这个基因是炎症过程中上调的可诱导前列腺素G/H合酶家族成员。这个基因的异常调控与几种组织中的癌症进展和心血管疾病风险的增加有关。这个基因是许多非甾体抗炎药物的作用靶点。[RefSeq, 2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Ptgs2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
