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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Prpf8 - pre-mRNA processing factor 8
Alias:
Prp8
Sfprp8l
DBF3/PRP8
D11Bwg0410e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因预测具有以下功能:K63链接的多泛素修饰依赖的蛋白质结合活性;pre-mRNA内含子结合活性;snRNA结合活性。参与细胞对脂多糖的反应;细胞对肿瘤坏死因子的反应;以及剪接体三snRNP复合体的组装。在mRNA剪接的上游或内部发挥作用,通过剪接体。定位在细胞核中。是U2型剪接体复合物和剪接体snRNP复合物的一部分。在包括中枢神经系统;生殖腺;和感觉器官在内的几个结构中表达。用于研究视网膜色素变性13。这个基因的人类同源物与视网膜色素变性13有关。与人类PRPF8(pre-mRNA加工因子8)正交。
Related ID:
NCBI:192159
ENSEMBL:ENSMUSG00000020850
UNIPROT:Q99PV0
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
192159
1
42
22671 bp
273.62
8
13
Prpf8 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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