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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pten - phosphatase and tensin homolog
Alias:
TEP1
MMAC1
PTENbeta
2310035O07Rik
A130070J02Rik
B430203M17Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有对抗磷脂和蛋白质的双重活性的磷酸酶,并起到肿瘤抑制因子作用。该蛋白质包含四个结构域:一个PIP2结合结构域,一个催化张力蛋白型磷酸酶结构域,一个C2张力蛋白型结构域和一个PDZ结合结构域。该蛋白质属于蛋白质酪氨酸磷酸酶家族。在小鼠中删除这个基因有助于多种组织的肿瘤发生。[由RefSeq,2015年9月提供]
Related ID:
NCBI:19211
ENSEMBL:ENSMUSG00000013663
UNIPROT:O08586
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19211
2
9
68584 bp
47.15
39
20
Pten Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
Gene Expression
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