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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pspn - persephin
Alias:
PSP
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个GDNF(胶质细胞系衍生神经营养因子)亚家族和TGF-beta(转化生长因子-beta)蛋白质超家族的分泌配体。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白。这种蛋白质通过RET受体酪氨酸激酶和一个GPI连接的核心受体发出信号,并促进神经元群体的生存。这种蛋白质可能在细胞死亡、神经系统发育和功能中发挥作用。缺乏这个基因功能拷贝的小鼠对脑缺血的敏感性增加。[RefSeq,2016年8月提供]
Related ID:
NCBI:19197
ENSEMBL:ENSMUSG00000002664
UNIPROT:O70300
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
19197
1
2
853 bp
Unknown
1
2
Pspn Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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References Literature
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